Basic Information
| LncRNA/CircRNA Name | MEG3 |
| Synonyms | NA |
| Region | GRCh38_14:100779410-100861031 |
| Ensemble | ENSG00000214548 |
| Refseq | NR_002766 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | CRC tissues, colorectal cancer cell lines (HCT116 and SW480) |
| Expression Pattern | down-regulated |
| Function Description | Consistent with previous reports, 91H and PVT-1 were up-regulated in cancer cell lines compared to normal control cells while MEG3 was down-regulated in cancer cell lines. |
| Pubmed ID | 30978169 |
| Year | 2019 |
| Title | A pilot study of new promising non-coding RNA diagnostic biomarkers for early-stage colorectal cancers. |
External Links
| Links for MEG3 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |