Basic Information
| LncRNA/CircRNA Name | MCM3AP-AS1 |
| Synonyms | NA |
| Region | GRCh38_21:46229217-46259390 |
| Ensemble | ENSG00000215424 |
| Refseq | NR_002776 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Luciferase reporter assay |
| Sample | HCC tissue,cell lines |
| Expression Pattern | up-regulated |
| Function Description | We revealed a novel oncogenic lncRNA MCM3AP-AS1, which is overexpressed in HCC and positively correlated with large tumor size, high tumor grade, advanced tumor stage and poor prognosis of HCC patients. |
| Pubmed ID | 30782188 |
| Year | 2019 |
| Title | A novel lncRNA MCM3AP-AS1 promotes the growth of hepatocellular carcinoma by targeting miR-194-5p/FOXA1 axis. |
External Links
| Links for MCM3AP-AS1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |