Basic Information
| LncRNA/CircRNA Name | MAPT-AS1 |
| Synonyms | NA |
| Region | GRCh38_17:45799390-45895630 |
| Ensemble | ENSG00000264589 |
| Refseq | NR_024559 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | other |
| Sample | TCGA,GEO |
| Expression Pattern | up-regulated |
| Function Description | A signature consisting of four lncRNAs, including PVT1, MAPT-AS1, LINC00667 and LINC00938, was identified, and patients were subsequently divided into high- and low-risk groups according to the median risk score. Kaplan-Meier analysis confirmed that patients in the high-risk group exhibited significantly poorer overall survival rate in both the training (P=0.0151) and the validation set (P=0.0016); furthermore, ROC analysis confirmed that the model could predict patient survival with a certain sensitivity and specificity. |
| Pubmed ID | 31897133 |
| Year | 2020 |
| Title | Identification of a Four-Long Non-Coding RNA Signature in Predicting Breast Cancer Survival |
External Links
| Links for MAPT-AS1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |