Basic Information
| LncRNA/CircRNA Name | MANCR |
| Synonyms | mitotically associated long non-coding RNA |
| Region | GRCh38_10:4650185-4678154 |
| Ensemble | ENSG00000231298 |
| Refseq | NR_024475 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | RT-qPCR |
| Sample | GC tissue specimens,GC cell lines HGC-27 and SNU-1 |
| Expression Pattern | up-regulated |
| Function Description | MANCR was upregulated in GC tissues compared with non-cancerous tissues. MANCR expression was not affected by clinical stages and a high MANCR expression level was associated with poor survival time.MANCR overexpression promoted, while miR-101 overexpression inhibited GC cell proliferation. |
| Pubmed ID | 31807188 |
| Year | 2019 |
| Title | Upregulation of MANCR Predicts Poor Survival in Patients With Gastric Cancer |
External Links
| Links for MANCR | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |