Basic Information
| LncRNA/CircRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853 |
| Region | GRCh38_11:65497688-65506516 |
| Ensemble | ENSG00000251562 |
| Refseq | NR_002819 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | qRT-PCR ect. |
| Sample | PTC tissues, thyroid nodule tissue |
| Expression Pattern | up-regulated |
| Function Description | MALAT1 expression was upregulated in PTC tissues compared with paired corresponding noncancerous tissues. We also found that upregulated MALAT1 expression was correlated with tumor size, lymph node metastases (p =?0.011) and WHO disease stage. |
| Pubmed ID | 29987950 |
| Year | 2018 |
| Title | Upregulation of long noncoding RNA MALAT1 in papillary thyroid cancer and its diagnostic value. |
External Links
| Links for MALAT1 | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |