Basic Information
| LncRNA/CircRNA Name | BA318C17.1 |
| Synonyms | MACROD2-AS1, BA318C17.1, NCRNA00186 |
| Region | GRCh38_20:14884253-14929515 |
| Ensemble | ENSG00000235914 |
| Refseq | NR_037841 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, STS-PCR, ISH etc. |
| Sample | primary CRC tissues, cell lines (Co1o205, Co1o320 HSR, Co1o678, Co1o741, HCA7, HCA46, HRA19, LS1034 etc.) |
| Expression Pattern | down-regulated |
| Function Description | Two noncoding RNA genes located in the region, BA318C17.1 and DJ974N19.1, were investigated by mutation analysis and real-time PCR in colorectal cancer cell lines. Sequence changes in BA318C17.1 and reduced expression of both genes was detected, suggesting that the abrogation of these genes may play a role in colorectal tumorigenesis. |
| Pubmed ID | 16110499 |
| Year | 2005 |
| Title | Deletion at chromosome band 20p12.1 in colorectal cancer revealed by high resolution array comparative genomic hybridization. |
External Links
| Links for BA318C17.1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |