Basic Information
| LncRNA/CircRNA Name | B3GALT5-AS1 |
| Synonyms | NA |
| Region | GRCh38_21:39597147-39612821 |
| Ensemble | ENSG00000184809 |
| Refseq | NR_026542 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR etc |
| Sample | serum samples |
| Expression Pattern | down-regulated |
| Function Description | The level of B3GALT5-AS1 in CRC patients was significantly lower than that of healthy patients (p < 0.0001). Further exploration validated that high serum B3GALT5-AS1 level was related to tumor node metastasis (TNM) stage (p = 0.008) and histological differentiation (p = 0.027). Compared with the healthy control group, AUCROC?of serum B3GALT5-AS1 in the CRC group was 0.762 with 95% CI: 0.698-0.826 (p < 0.0001). |
| Pubmed ID | 32207329 |
| Year | 2020 |
| Title | Serum Level of Long Noncoding RNA B3GALT5-AS1 as a Diagnostic Biomarker of Colorectal Cancer |
External Links
| Links for B3GALT5-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |