Basic Information
| LncRNA/CircRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853 |
| Region | GRCh38_11:65497688-65506516 |
| Ensemble | ENSG00000251562 |
| Refseq | NR_002819 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | adrenocortical carcinoma |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR etc. |
| Sample | ACC tissues |
| Expression Pattern | up-regulated |
| Function Description | MALAT1, DLX6-AS1 and LOC100131320 were found in the microarray to be overexpressed in ACC. This was confirmed by qRT-PCR in the validation cohort, with these lncRNAs also overexpressed. CREM and PRINS expression was down-regulated in ACC by microarray and also by qRT-PCR. |
| Pubmed ID | 25595289 |
| Year | 2015 |
| Title | Long noncoding RNA profiles of adrenocortical cancer can be used to predict recurrence. |
External Links
| Links for MALAT1 | GenBank HGNC NONCODE |
| Links for adrenocortical carcinoma | OMIM COSMIC |