Basic Information
| LncRNA/CircRNA Name | MALAT1 |
| Synonyms | MALAT1, HCN, LINC00047, NCRNA00047, NEAT2, PRO2853 |
| Region | GRCh38_11:65497688-65506516 |
| Ensemble | ENSG00000251562 |
| Refseq | NR_002819 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | vulvar squamous cell carcinoma |
| ICD-0-3 | C52.9 |
| Methods | Microarray, qPCR etc. |
| Sample | VSCC tissues |
| Expression Pattern | down-regulated |
| Function Description | A general consistency between the microarray and real-time PCR showed that the six selected lncRNAs were dysregulated between VSCC tissues and the control group. The levels of HOTAIR, MALAT1, MEG3 and LINC00478 expression were decreased and NEAT1 was upregulated as indicated by the microarray analysis. |
| Pubmed ID | 27633334 |
| Year | 2016 |
| Title | Long non-coding RNA expression profile in vulvar squamous cell carcinoma and its clinical significance. |
External Links
| Links for MALAT1 | GenBank HGNC NONCODE |
| Links for vulvar squamous cell carcinoma | OMIM COSMIC |