Basic Information
LncRNA/CircRNA Name | MALAT1 |
Synonyms | NA |
Region | GRCh38_11:65497688-65506516 |
Ensemble | ENSG00000251562 |
Refseq | NR_002819 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | Cisplatin, Adriamycin, Gefitinib and Paclitaxel | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | non small cell lung cancer |
ICD-0-3 | C34 |
Methods | qPCR |
Sample | NSCLC tissue, cell lines(A549, H1299, SPC-A-1,H460) |
Expression Pattern | up-regulated |
Function Description | Our results indicated that MALAT1 and miR-197-3p were both over-expressed within NSCLC tissues and cells, when compared with normal tissues and cells |
Pubmed ID | 30841025 |
Year | 2019 |
Title | LncRNA MALAT1 Depressed Chemo-Sensitivity of NSCLC Cells through Directly Functioning on miR-197-3p/p120 Catenin Axis. |
External Links
Links for MALAT1 | GenBank HGNC NONCODE |
Links for non small cell lung cancer | OMIM COSMIC |