Basic Information
| LncRNA/CircRNA Name | MALAT1 |
| Synonyms | NA |
| Region | GRCh38_11:65497688-65506516 |
| Ensemble | ENSG00000251562 |
| Refseq | NR_002819 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qRT-PCR, Western blot |
| Sample | cervical carcinoma tissues,cell lines(C-33A, Ca Ski, HeLa and SiHa) |
| Expression Pattern | up-regulated |
| Function Description | MALAT1 as the competitive endogenous long non-coding RNA for miR-625-5p, and over-expression of MALAT1 attenuated the inhibitory effect of miR-625-5p on NF-?B signaling in cervical carcinoma. |
| Pubmed ID | 32152961 |
| Year | 2020 |
| Title | MicroRNA-625-5p Sponges lncRNA MALAT1 to Inhibit Cervical Carcinoma Cell Growth by Suppressing NF-?B Signaling |
External Links
| Links for MALAT1 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |