Basic Information
| LncRNA/CircRNA Name | LUCAT1 |
| Synonyms | LUCAT1, SCAL1 |
| Region | GRCh38_5:91303029-91314402 |
| Ensemble | ENSG00000248323 |
| Refseq | NR_103548 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Luciferase reporter assay, in vitro knockdown etc. |
| Sample | cell lines (LN229, U251, SNB19, U87, H4), glioma tissues |
| Expression Pattern | up-regulated |
| Function Description | LUCAT1 was substantially upregulated in glioma tissues and cells.LUCAT1 inhibition significantly suppressed the proliferation and invasion of glioma cells. The lncRNA LUCAT1 was critical for the proliferation and invasion of glioma cells by regulating miR-375. |
| Pubmed ID | 29089067 |
| Year | 2017 |
| Title | Knockdown of Long Noncoding RNA LUCAT1 Inhibits Cell Viability and Invasion by Regulating miR-375 in Glioma. |
External Links
| Links for LUCAT1 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |