Basic Information
| LncRNA/CircRNA Name | LUADT1 |
| Synonyms | Lung adenocarcinoma associated transcript 1 |
| Region | GRCh38_6:147158925-147180992 |
| Ensemble | ENSG00000196634 |
| Refseq | NR_132442 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | small cell lung cancer |
| ICD-0-3 | C56.9 |
| Methods | RT-qPCR, Western blot |
| Sample | tumor (SCLC) and non-tumor tissue,SHP-77 and H69 human SCLC cell lines |
| Expression Pattern | up-regulated |
| Function Description | LUADT1 and Twist1 were upregulated in SCLC, while miR-15a-3p was downregulated in SCLC.LUADT1 may sponge miR-15a-3p to upregulate Twist1 in SCLC, thereby promoting cancer cell invasion and migration. |
| Pubmed ID | 31842825 |
| Year | 2019 |
| Title | LncRNA LUADT1 Sponges miR-15a-3p to Upregulate Twist1 in Small Cell Lung Cancer |
External Links
| Links for LUADT1 | GenBank HGNC NONCODE |
| Links for small cell lung cancer | OMIM COSMIC |