Basic Information
| LncRNA/CircRNA Name | LSINCT6 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Northern blot etc. |
| Sample | cell lines (HMEC, HCC1500, HCC1569 etc.) |
| Expression Pattern | up-regulated |
| Function Description | Collectively, our results identified a new class of long stress responsive non-coding transcripts, LSINCTs, which have increased expression in response to DNA damage induced by NNK. LSINCTs interestingly also have increased expression in a number of cancer-derived cell lines, indicating that the expression is increased in both, correlating cellular stress and cancer. |
| Pubmed ID | 20214974 |
| Year | 2010 |
| Title | Identification of long stress-induced non-coding transcripts that have altered expression in cancer. |
External Links
| Links for LSINCT6 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |