Basic Information
| LncRNA/CircRNA Name | LOXL1-AS1 |
| Synonyms | NA |
| Region | GRCh38_15:73908071-73928248 |
| Ensemble | ENSG00000261801 |
| Refseq | NR_040066 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, RNA-seq |
| Sample | osteosarcoma tissues,cell lines (MG63, U-2 OS, Saos-2, HOS , hFOB1.19) |
| Expression Pattern | up-regulated |
| Function Description | LOXL1-AS1 overexpression acted as an independent poor predictor for overall survival in osteosarcoma patients. |
| Pubmed ID | 30944201 |
| Year | 2019 |
| Title | LOXL1-AS1 predicts poor prognosis and promotes cell proliferation, migration, and invasion in osteosarcoma. |
External Links
| Links for LOXL1-AS1 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |