Basic Information
| LncRNA/CircRNA Name | LOC84740 |
| Synonyms | AFAP1-AS1, AFAP1-AS, AFAP1AS, LOC84740 |
| Region | GRCh38_4:7754090-7778928 |
| Ensemble | ENSG00000272620 |
| Refseq | NR_026892 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | Microarray, qPCR etc. |
| Sample | NPC tissues |
| Expression Pattern | up-regulated |
| Function Description | All four lncRNAs (LOC84740, ENST00000498296, AL359062, and ENST00000438550) were differentially expressed in the metastatic and primary NPC tumors based on microarray analysis, which was validated via QPCR using the same tissues. The validation results of the four lncRNAs indicated that the microarray data strongly correlated with the QPCR results. These lncRNAs displayed higher expression levels in NPC primary tumors with progression than in those without progression. |
| Pubmed ID | 26448942 |
| Year | 2015 |
| Title | Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value. |
External Links
| Links for LOC84740 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |