Basic Information
| LncRNA/CircRNA Name | LOC285758 |
| Synonyms | NA |
| Region | GRCh38_6:113868013-113873351 |
| Ensemble | ENSG00000227502 |
| Refseq | NR_038863 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot |
| Sample | AML cell lines,blood |
| Expression Pattern | up-regulated |
| Function Description | targeting of miR-204-5p by LOC285758 promotes the cell viability and invasion of AML cells, and thus, LOC285758 may have potential as a therapeutic target for AML treatment. |
| Pubmed ID | 32067385 |
| Year | 2020 |
| Title | The long non-coding RNA LOC285758 promotes invasion of acute myeloid leukemia cells by down-regulating miR-204-5p |
External Links
| Links for LOC285758 | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |