Basic Information
| LncRNA/CircRNA Name | LOC100133669 |
| Synonyms | NA |
| Region | GRCh38_8:142981738-143018437 |
| Ensemble | ENSG00000247317 |
| Refseq | NR_026913 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | oesophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | RT-qPCR, Western blot |
| Sample | ESCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | LOC100133669 could bind to Tim50 and upregulated its protein level through inhibiting ubiquitination. Overexpression of Tim50 in part abolished the LOC100133669 depletion-caused inhibitory effect on ESCC cell proliferation. |
| Pubmed ID | 32130753 |
| Year | 2019 |
| Title | Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma |
External Links
| Links for LOC100133669 | GenBank HGNC NONCODE |
| Links for oesophageal squamous cell carcinoma | OMIM COSMIC |