Basic Information
| LncRNA/CircRNA Name | ZNF674-1 |
| Synonyms | ZNF674, MRX92, ZNF673B |
| Region | GRCh38_X:46497727-46545457 |
| Ensemble | ENSG00000251192 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR etc. |
| Sample | nasopharyngeal cancer tissues, cell lines |
| Expression Pattern | up-regulated |
| Function Description | When the expression of lncRNA ZNF674-1 was reduced in NPC cells, the proliferation, migration and invasion of these cells was promoted, whereas the apoptosis of these cells was decreased. |
| Pubmed ID | 29805695 |
| Year | 2018 |
| Title | Long non-coding RNA ZNF674-1 acts as a cancer suppressor in nasopharyngeal carcinoma |
External Links
| Links for ZNF674-1 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |