Basic Information
| LncRNA/CircRNA Name | lncTIC1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | CRISPR, qPCR, western blot etc. |
| Sample | liver cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Here, we performed unbiased screening of lncRNAs in liver tumorigenesis and found lncTIC1 was highly expressed with liver tumorigenesis. Meanwhile, lncTIC1 expression levels were related to liver cancer relapse, metastasis and clinical prognosis. |
| Pubmed ID | 29778568 |
| Year | 2018 |
| Title | LncTIC1 interacts with ?-catenin to drive liver TIC self-renewal and liver tumorigenesis |
External Links
| Links for lncTIC1 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |