Basic Information
| LncRNA/CircRNA Name | lnc-SPRR2D-1 |
| Synonyms | LINC01527, lnc-SPRR2D-1 |
| Region | GRCh38_1:152930040-152949210 |
| Ensemble | ENSG00000224308 |
| Refseq | XR_241125 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | tongue squamous cell carcinoma |
| ICD-0-3 | C02 |
| Methods | Microarray, qPCR etc. |
| Sample | TSCC tissues |
| Expression Pattern | up-regulated |
| Function Description | Overexpression of lnc-SPRR2D-1 and lnc-PPP2R4-5 was found in the tongue SCC tissue. Overexpression of the lnc-MBL2-4:3 in the tongue SCC was highly significant in comparison with the paired normal epithelia. Lnc-AL355149.1-1 was the only lncRNA found to be downregulated in the tongue SCC tissues.The association of lncRNA with the T-stage and nodal status of tongue SCC patients suggested that lncRNA deregulation was involved in the pathogenesis of tongue SCC. |
| Pubmed ID | 25045670 |
| Year | 2014 |
| Title | Long non-coding RNA deregulation in tongue squamous cell carcinoma. |
External Links
| Links for lnc-SPRR2D-1 | GenBank HGNC NONCODE |
| Links for tongue squamous cell carcinoma | OMIM COSMIC |