Basic Information
| LncRNA/CircRNA Name | lnc-Sox5 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | tongue cancer |
| ICD-0-3 | C02 |
| Methods | qPCR, Western blot, RIP |
| Sample | tongue carcinogenesis tissues, cell lines (HEK-293, HeLa, U266) |
| Expression Pattern | up-regulated |
| Function Description | In this study, we report an ultra-highly expressed lncRNA, lnc-Sox5, in tongue tumor tissues. The results imply that lnc-Sox5 may play vital role in tongue carcinoma progression. We observed that the growth of Tca8113 cells was suppressed by lnc-Sox5 downregulation. |
| Pubmed ID | 28371600 |
| Year | 2017 |
| Title | HuR Stabilizes lnc-Sox5 mRNA to Promote Tongue Carcinogenesis |
External Links
| Links for lnc-Sox5 | GenBank HGNC NONCODE |
| Links for tongue cancer | OMIM COSMIC |