Basic Information
| LncRNA/CircRNA Name | lncRNA-WRAP53 |
| Synonyms | WRAP53, DKCB3, TCAB1, WDR79 |
| Region | GRCh38_17:7686071-7703502 |
| Ensemble | ENSG00000141499 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR etc. |
| Sample | HCC tissues |
| Expression Pattern | up-regulated |
| Function Description | We found that lncRNA-UCA1 and lncRNA-WRAP53 were significantly higher in sera of HCC than those with chronic HCV infection or healthy volunteers. Our data suggested that the increased expression of UCA1 and WRAP53 was associated with advanced clinical parameters in HCC. |
| Pubmed ID | 26551349 |
| Year | 2015 |
| Title | Investigation of long noncoding RNAs expression profile as potential serum biomarkers in patients with hepatocellular carcinoma. |
External Links
| Links for lncRNA-WRAP53 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |