Basic Information
| LncRNA/CircRNA Name | lncRNA-URHC |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot etc. |
| Sample | cell line |
| Expression Pattern | up-regulated |
| Function Description | LncRNA-URHC expression was significantly increased in colorectal cancer cells compared with normal cells, and the expression of lncRNA-URHC in colorectal cancer cells was higher than that in the normal cell. After down-regulated the expression of lncRNA-URHC, the proliferation and invasion of colorectal cancer cells were decreased, while cells apoptosis was promoted. Down-regulation of lncRNA-URHC could enhance the expression of E-cadherin and reduce the expression of N-cadherin, vimentin and snail. |
| Pubmed ID | 29630109 |
| Year | 2018 |
| Title | Effects of long non-coding RNA URHC on proliferation, apoptosis and invasion of colorectal cancer cells. |
External Links
| Links for lncRNA-URHC | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |