Basic Information
LncRNA/CircRNA Name | LINCRNA-p21 |
Synonyms | TP53COR1, TRP53COR1, linc-p21, lincRNA-p21 |
Region | NA |
Ensemble | NA |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | brown seaweed oligo-fucoidan | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | Hepatocellular carcinoma |
ICD-0-3 | C22.0 |
Methods | qPCR, Western blot, in vitro knockdown, etc. |
Sample | HepG2 cell, the human liver cancer cell line |
Expression Pattern | differential expression |
Function Description | lncRNAs switched oligofucoidan- induced apoptosis, which might be potentially valuable in HCC adjuvant therapy. |
Pubmed ID | 30632031 |
Year | 2019 |
Title | The anti-tumor activity of brown seaweed oligo-fucoidan via lncRNA expression modulation in HepG2 cells |
External Links
Links for LINCRNA-p21 | GenBank HGNC NONCODE |
Links for Hepatocellular carcinoma | OMIM COSMIC |