Basic Information
| LncRNA/CircRNA Name | lncRNA-PE |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot, RNAi |
| Sample | hepatocellular carcinoma tissues, cell lines (BEL-7402 and SK-Hep-1) |
| Expression Pattern | differential expression |
| Function Description | Further study suggested that lncRNA-PE downregulated miR-200a/b by repressing the primary transcript expression, enhanced ZEB1 expression, and promoted epithelial-mesenchymal transition of hepatocellular carcinoma cells. |
| Pubmed ID | 28488544 |
| Year | 2017 |
| Title | A long non-coding RNA lncRNA-PE promotes invasion and epithelial-mesenchymal transition in hepatocellular carcinoma through the miR-200a/b-ZEB1 pathway |
External Links
| Links for lncRNA-PE | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |