Basic Information
| LncRNA/CircRNA Name | ABHD11-AS1 |
| Synonyms | ABHD11-AS1, LINC00035, NCRNA00035, WBSCR26 |
| Region | GRCh38_7:73735038-73736158 |
| Ensemble | ENSG00000225969 |
| Refseq | NR_026690 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot |
| Sample | ovarian cancer tissue, ovarian carcinoma cell lines (A2780 ,OVCAR3) |
| Expression Pattern | up-regulated |
| Function Description | This is the first study to demonstrate the role of RhoC in the tumor-promoting effects of the lncRNA ABHD11-AS1. The present findings shed light on new therapeutic targets for ovarian cancer treatment.Because of its hidden onset, poor prognosis and high fatality rate, the overall survival rate of this cancer is not satisfactory. |
| Pubmed ID | 28818073 |
| Year | 2017 |
| Title | Role of the lncRNA ABHD11-AS1 in the tumorigenesis and progression of epithelial ovarian cancer through targeted regulation of RhoC. |
External Links
| Links for ABHD11-AS1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |