Basic Information
| LncRNA/CircRNA Name | lncRNA-LET |
| Synonyms | NPTN-IT1, lncRNA-LET |
| Region | GRCh38_15:73567012-73569294 |
| Ensemble | ENSG00000281183 |
| Refseq | NR_103844 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR, Western blot, RIP etc. |
| Sample | nasopharyngeal carcinoma tissues, cell lines (CNE1, CNE2, SUNE1, HNE1, HONE1 and C666-1) |
| Expression Pattern | down-regulated |
| Function Description | Our research found that there was less expression of LET in nasopharyngeal carcinoma (NPC) tissues than normal tissues and that LET might inhibit proliferation, adhesion and invasion of NPC in vitro by enhancing its expression. |
| Pubmed ID | 28615956 |
| Year | 2017 |
| Title | The role of long noncoding RNA-LET in cell proliferation and invasion of nasopharyngeal carcinoma and its mechanism |
External Links
| Links for lncRNA-LET | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |