Basic Information
| LncRNA/CircRNA Name | lncRNA-BCHE |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Microarray, etc. |
| Sample | breast cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | lncRNA-BCHE is an oncogenic lncRNA enhancing the growth and metastatic potential of breast cancer cells. All breast cancer patients were subdivided into ITGB1low and ITGB1 high groups based on their ITGB1 transcript levels, and their distant metastasis-free survival (DMFS) and relapse-free survival (RFS) probability were plotted over time. In all patients, low ITGB1 gene expression was associated with a superior DMFS and RFS probability relative to the corresponding ITGB1 high group, |
| Pubmed ID | 29948648 |
| Year | 2018 |
| Title | Long non-coding RNA p10247, high expressed in breast cancer (lncRNA-BCHE), is correlated with metastasis. |
External Links
| Links for lncRNA-BCHE | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |