Basic Information
| LncRNA/CircRNA Name | ASB16-AS1 |
| Synonyms | NA |
| Region | GRCh38_17:44175973-44186717 |
| Ensemble | ENSG00000267080 |
| Refseq | NR_049729 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR, Dual Luciferase Reporter Assay |
| Sample | HCC samples,HCC cell lines and LO2 cells |
| Expression Pattern | up-regulated |
| Function Description | ASB16-AS1 was overexpressed in HCC tissues.Functional studies showed ASB16-AS1 knockdown attenuated proliferation, migration and invasion of HCC cells. Mechanistically, ASB16-AS1 directly interacted with miR-1827 and promoted FZD4 expression by sponging miR-1827. |
| Pubmed ID | 31807066 |
| Year | 2019 |
| Title | LncRNA ASB16-AS1 Promotes Growth And Invasion Of Hepatocellular Carcinoma Through Regulating miR-1827/FZD4 Axis And Activating Wnt/?-Catenin Pathway |
External Links
| Links for ASB16-AS1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |