Basic Information
| LncRNA/CircRNA Name | ASB16-AS1 |
| Synonyms | ASB16 antisense RNA 1 |
| Region | GRCh38_17:44175973-44186717 |
| Ensemble | ENSG00000267080 |
| Refseq | NR_049729 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc |
| Sample | OS tissues, cell lines (HOS, 143B, MG-63, U2OS, and SAOS-2) |
| Expression Pattern | up-regulated |
| Function Description | ASB16-AS1 expression was significantly elevated in OS tissues and cell lines, and increased ASB16-AS1 expression was related to patients' tumor size, TNM stage, and distant metastasis. The overall survival rate of OS patients presenting high ASB16-AS1 expression was shorter than that of patients presenting low ASB16-AS1 expression. |
| Pubmed ID | 32214826 |
| Year | 2020 |
| Title | Long Non-Coding RNA ASB16-AS1 Functions as a miR-760 Sponge to Facilitate the Malignant Phenotype of Osteosarcoma by Increasing HDGF Expression |
External Links
| Links for ASB16-AS1 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |