Basic Information
| LncRNA/CircRNA Name | lncRNA799 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot, Luciferase reporter assay, other |
| Sample | cervical cancer tissues and cell line (SiHa and C33a) |
| Expression Pattern | up-regulated |
| Function Description | Overexpression of lncRNA799 was found to have a significant correlation with FIGO stage, SCC-Ag level, and lymphatic metastasis, and it was also associated with poor survival. Ectopic expression of lncRNA799 promoted the metastasis of SiHa cells, whereas lncRNA799 knockdown had an inhibitory effect on metastasis.Moreover, lncRNA799 modulated the expression of TBL1XR1 by acting as a competitive endogenous RNA (ceRNA) for miR-454-3P. |
| Pubmed ID | 30439646 |
| Year | 2018 |
| Title | Role of Long Noncoding RNA 799 in the Metastasis of Cervical Cancer Through Upregulation of TBL1XR1 Expression |
External Links
| Links for lncRNA799 | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |