Basic Information
| LncRNA/CircRNA Name | lnc-OC1 |
| Synonyms | FRP,FSL1,OCC1,OCC-1,tsc36,MIR198 |
| Region | GRCh38_3:120392293-120451253 |
| Ensemble | ENSG00000163430 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot, RIP, Microarray, etc. |
| Sample | cell lines (Caco-2, HCT116, HT-29, RKO, SW480, SW620 ,HEK-293T) |
| Expression Pattern | down-regulated |
| Function Description | LncRNA OCC-1 can regulate the levels of a large number of mRNAs at post-transcriptional level through modulating RBP HuR stability. |
| Pubmed ID | 29931370 |
| Year | 2018 |
| Title | Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer. |
External Links
| Links for lnc-OC1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |