Basic Information
LncRNA/CircRNA Name | lncNEN885 |
Synonyms | NA |
Region | NA |
Ensemble | NA |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | Gastroenteropancreatic Neuroendocrine Neoplasms |
ICD-0-3 | NA |
Methods | qPCR, Western blot |
Sample | gastroenteropancreatic neuroendocrine neoplasms tissues, cell lines(BON-1, LCC-18) |
Expression Pattern | down-regulated |
Function Description | we found that lncNEN885 was markedly decreased in human gastric NEN samples compared to adjacent normal tissues by transcriptome sequencing. dysregulation of lncNEN885 can regulate cell migration and invasion by activating epithelial-mesenchymal transition process partially through canonical Wnt/?-catenin signaling in GEP-NEN cells. |
Pubmed ID | 30033597 |
Year | 2018 |
Title | LncNEN885 Inhibits Epithelial-Mesenchymal Transition by Partially Regulation of Wnt/?-catenin Signalling in Gastroenteropancreatic Neuroendocrine Neoplasms. |
External Links
Links for lncNEN885 | GenBank HGNC NONCODE |
Links for Gastroenteropancreatic Neuroendocrine Neoplasms | OMIM COSMIC |