Basic Information
| LncRNA/CircRNA Name | lncMAPK6 |
| Synonyms | NA |
| Region | GRCh38_15:51952106-52067372 |
| Ensemble | ENSG00000069956 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | Luciferase reporter assay etc. |
| Sample | liver cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | MAPK6 was the most highly expressed MAPK component in liver cancer and liver TICs and lncMAPK6 participated in the transcriptional regulation of MAPK6in cis. This work revealed the importance role of MAPK signaling in liver TIC self-renewal and added a new layer for liver TIC and MAPK6 expression regulation. |
| Pubmed ID | 29764463 |
| Year | 2018 |
| Title | LncMAPK6 drives MAPK6 expression and liver TIC self-renewal. |
External Links
| Links for lncMAPK6 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |