Basic Information
| LncRNA/CircRNA Name | lnc-LIF-AS |
| Synonyms | NA |
| Region | GRCh38_22:30239194-30240538 |
| Ensemble | ENSG00000232530 |
| Refseq | NR_149070 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | RT-PCR , Western blot etc. |
| Sample | cervical cancer tissues and normal tissues ,cervical cancer cell lines(SiHa, ME-180, C-33A, HeLa, 293T, and HaCat) |
| Expression Pattern | up-regulated |
| Function Description | In the SiHa/con and SiHa/Lnc-LIF-AS-DN cell groups, there were no significant differences in cell proliferation, cell migration and cell invasion. The overexpression of Lnc-LIF-AS can promote cell proliferation, migration and invasion in cervical cancer cells, and the core function domain of this lncRNA was located in the overlapping a 3'-UTR base sequence of LIF mRNA. |
| Pubmed ID | 31085454 |
| Year | 2019 |
| Title | Effects of LncRNA Lnc-LIF-AS on Cell Proliferation, Migration and Invasion in a Human Cervical Cancer Cell Line |
External Links
| Links for lnc-LIF-AS | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |