Basic Information
| LncRNA/CircRNA Name | lnc-LCE5A-1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal cancer |
| ICD-0-3 | C32 |
| Methods | RNA-seq, qPCR etc. |
| Sample | cell lines (UMSCC-22B) |
| Expression Pattern | down-regulated |
| Function Description | We confirmed the dysregulation of these noncoding RNAs in head and neck cancer cell lines derived from different anatomic sites, and determined that ectopic expression of the two lncRNAs inhibited key EMT and stem cell genes and reduced cellular proliferation and migration. |
| Pubmed ID | 25904139 |
| Year | 2015 |
| Title | Transcriptome sequencing uncovers novel long noncoding and small nucleolar RNAs dysregulated in head and neck squamous cell carcinoma. |
External Links
| Links for lnc-LCE5A-1 | GenBank HGNC NONCODE |
| Links for laryngeal cancer | OMIM COSMIC |