Basic Information
| LncRNA/CircRNA Name | lnc-JPH1-7 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | head and neck squamous cell carcinoma |
| ICD-0-3 | C76.0 |
| Methods | qPCR, RNAi etc. |
| Sample | cell lines (UMSCC-10B, UMSCC-22B, HN-1, HN-12, HN-30, SCC-4, Cal-27 etc.) |
| Expression Pattern | up-regulated |
| Function Description | We found that elevated lnc-JPH1-7 levels in HNSCCs associated not only with poor prognosis, methyltransferase KMT2D (MLL1) mutation, and concurrent TP53 mutation and 3p deletion, but also significantly correlated to advanced tumor stage. Furthermore, higher median lnc-JPH1-7 expression was observed among HPVnegative patients and patients reporting history of smoking. |
| Pubmed ID | 27323410 |
| Year | 2016 |
| Title | The non-coding landscape of head and neck squamous cell carcinoma. |
External Links
| Links for lnc-JPH1-7 | GenBank HGNC NONCODE |
| Links for head and neck squamous cell carcinoma | OMIM COSMIC |