Basic Information
| LncRNA/CircRNA Name | HOST2 |
| Synonyms | CERNA2, HOST2, lncRNA-HOST2 |
| Region | GRCh38_1:29554-31109 |
| Ensemble | |
| Refseq | NR_134505 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot etc. |
| Sample | ovarian cancer tissues, cells lines (OVCAR3) |
| Expression Pattern | up-regulated |
| Function Description | The data showed that HOST2 was obviously upregulated in an EOCderived cell line, OVCAR-3, compared with the other tested cell lines, including MKN28, Huh-7, HepG2, McF-7,DU145, A357, MG63, Hep-2, ARK2 and Hela. HOST2 promotes tumor cell migration, invasion and proliferation in epithelial ovarian cancer by working in key aspetcs of biological behaviors. |
| Pubmed ID | 25292198 |
| Year | 2014 |
| Title | LncRNA-HOST2 regulates cell biological behaviors in epithelial ovarian cancer through a mechanism involving microRNA let-7b. |
External Links
| Links for HOST2 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |