Basic Information
| LncRNA/CircRNA Name | lncGPR107 |
| Synonyms | LncGPR107 |
| Region | GRCh38_9:130140610-130144219 |
| Ensemble | ENSG00000196979 |
| Refseq | NR_135124 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot, ChIP, etc. |
| Sample | liver cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | LncGPR107 drove the self-renewal of liver TICs through GPR107. LncGPR107 participated in the transcriptional regulation of GPR107 in cis, through recruiting SRCAP remodeling complex to GPR107 promoter. the expression pattern of GPR107 was associated with liver tumor clinical characteristics, including metastasis, relapse and prognosis. |
| Pubmed ID | 29925408 |
| Year | 2018 |
| Title | LncGPR107 drives the self-renewal of liver tumor initiating cells and liver tumorigenesis through GPR107-dependent manner. |
External Links
| Links for lncGPR107 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |