Basic Information
| LncRNA/CircRNA Name | lnc-EPS15L1-2:1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | Microarray, qPCR |
| Sample | Human hepatocyte cell line QSG-7701 and human HCC cell lines SMMC-7721, HuH-7, HepG2, MHCC97H, MHCC-97L, and HCC-LM3, blood |
| Expression Pattern | up-regulated |
| Function Description | ENST00000418803, lnc-ZNF35-4:1, lnc-EPS15L1-2:1, BCLC stage, and vascular invasion were selected as components of the nomogram according to the adjusted multivariate analysis. Te nomogram efectively predicted the HCC LNM risk among the cohorts with suitable calibration fttings and displayed high discrimination with C-index of 0.89 and 0.85. Moreover, the abnormally high expression of lnc-EPS15L1-2:1 in HCC cell lines showed signifcant carcinogenic efects |
| Pubmed ID | 31355249 |
| Year | 2019 |
| Title | A Noninvasive Prediction Nomogram for Lymph Node Metastasis of Hepatocellular Carcinoma Based on Serum Long Noncoding RNAs |
External Links
| Links for lnc-EPS15L1-2:1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |