Basic Information
| LncRNA/CircRNA Name | lncBRM |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, RNAi, Western blot, Northern blot, ChIP etc. |
| Sample | HCC tissues, cell lines (Huh7, Hep3B and PLC) |
| Expression Pattern | up-regulated |
| Function Description | We observed that lncBRM was indeed highly expressed in liver CSCs derived from six HCC primary samples. We found that lncBRM was also highly expressed in oncosphere cells derived from HCC primary samples and cell lines. |
| Pubmed ID | 27905400 |
| Year | 2016 |
| Title | LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells. |
External Links
| Links for lncBRM | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |