Basic Information
| LncRNA/CircRNA Name | lnc-ACACA-1 |
| Synonyms | NA |
| Region | GRCh38_17:37084988-37406818 |
| Ensemble | ENSG00000278540 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | clear cell renal cell carcinoma |
| ICD-0-3 | C64.9 |
| Methods | Microarray, qPCR etc. |
| Sample | ccRCC tissues |
| Expression Pattern | down-regulated |
| Function Description | Among these, aberrant expression was validated using PCR: lnc-BMP2-2, lnc-CPN2-1, lnc-FZD1-2, lnc-ITPR2-3, lnc-SLC30A4-1, and lnc-SPAM1-6 were highly overexpressed in ccRCC, whereas lnc-ACACA-1, lnc-FOXG1-2, lnc-LCP2-2, lnc-RP3-368B9, and lnc-TTC34-3 were downregulated. Computational analyses revealed that these lncRNAs are involved in RNA-protein networks related to splicing, binding, transport, localization, and processing of RNA. |
| Pubmed ID | 25685243 |
| Year | 2015 |
| Title | Identification of novel long non-coding RNAs in clear cell renal cell carcinoma. |
External Links
| Links for lnc-ACACA-1 | GenBank HGNC NONCODE |
| Links for clear cell renal cell carcinoma | OMIM COSMIC |