Basic Information
| LncRNA/CircRNA Name | LINCRNA-p21 |
| Synonyms | TP53COR1, TRP53COR1, linc-p21, lincRNA-p21 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | head and neck cancer |
| ICD-0-3 | C76.0 |
| Methods | qPCR etc. |
| Sample | blood |
| Expression Pattern | down-regulated |
| Function Description | LincRNA-p21 and GAS5 levels were found to be significantly lower in plasma of the HNC patients than in healthy individuals with median values 0.008 vs. 0.571 and 0.126 vs. 0.910, respectively. |
| Pubmed ID | 26482616 |
| Year | 2016 |
| Title | Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy. |
External Links
| Links for LINCRNA-p21 | GenBank HGNC NONCODE |
| Links for head and neck cancer | OMIM COSMIC |