Basic Information
| LncRNA/CircRNA Name | LINCRNA-p21 |
| Synonyms | TP53COR1, TRP53COR1, linc-p21, lincRNA-p21 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | Breast Cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Western blot |
| Sample | MCF-7 cell line, MDA-MB231 cell line |
| Expression Pattern | differential expression |
| Function Description | Our results indicated that some of the lncRNAs having tumor suppressor (GAS5, MEG3, lincRNA-p21) and oncogenic roles (HOTAIR) are regulated by c-MYC. |
| Pubmed ID | 31326549 |
| Year | 2019 |
| Title | MYC-Driven Regulation of Long Non-Coding RNA profiles in Breast Cancer Cells |
External Links
| Links for LINCRNA-p21 | GenBank HGNC NONCODE |
| Links for Breast Cancer | OMIM COSMIC |