Basic Information
| LncRNA/CircRNA Name | LINCRNA02471 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc |
| Sample | PTC tissues,cell line(Nthy-ori 3-1, BCPAP, KTC-1, K1) |
| Expression Pattern | up-regulated |
| Function Description | LincRNA02471 was manifestly upregulated in papillary cancer tissues. Overexpression of lincRNA02471 significantly promoted the cell proliferation, invasion and inhibited cell apoptosis. Knockdown of lincRNA02471 inhibited the cancer development. We also found that lincRNA02471 negatively regulate miR-758 in papillary thyroid cancer. |
| Pubmed ID | 32194901 |
| Year | 2020 |
| Title | Overexpression of lincRNA02471 Promote Cancer Development Though miR-758/HIPK3 Signaling Pathway in Papillary Thyroid Cancer |
External Links
| Links for LINCRNA02471 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |