Basic Information
| LncRNA/CircRNA Name | LINC-PINT |
| Synonyms | NA |
| Region | GRCh38_7:130938963-131110176 |
| Ensemble | ENSG00000231721 |
| Refseq | NR_015431 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qRT-PCR, Western blot, RIP |
| Sample | NSCLC tissues |
| Expression Pattern | down-regulated |
| Function Description | LINC-PINT was obviously decreased in NSCLC.LINC-PINT repressed cell proliferation and cell colony formation of A549 and H1299 cells.LINC-PINT exerted crucial biological roles in NSCLC through sponging miR-543 and inducing PTEN. |
| Pubmed ID | 31981466 |
| Year | 2019 |
| Title | LINC-PINT alleviates lung cancer progression via sponging miR-543 and inducing PTEN |
External Links
| Links for LINC-PINT | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |