Basic Information
| LncRNA/CircRNA Name | LINC-OIP5 |
| Synonyms | OIP5-AS1, cyrano, linc-OIP5 |
| Region | GRCh38_15:41283990-41309737 |
| Ensemble | ENSG00000104147 |
| Refseq | NR_026757 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RT-qPCR |
| Sample | breast cancer tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | linc-OIP5 in MDA-MB-231 breast cancer cells may act on the upstream of the YAP1/Notch/NRP1 signaling circuit to affect proliferation, migration, and tube formation of co-cultured HUVECs in a non-cellular direct contact way through JAG1 in conditioned medium. |
| Pubmed ID | 32046779 |
| Year | 2020 |
| Title | Linc-OIP5 in?the?breast cancer cells regulates angiogenesis of?human umbilical vein endothelial cells through?YAP1/Notch/NRP1 signaling circuit at?a?tumor microenvironment |
External Links
| Links for LINC-OIP5 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |