Basic Information
LncRNA/CircRNA Name | LINCIN |
Synonyms | NA |
Region | NA |
Ensemble | NA |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR, Western blot etc. |
Sample | breast cancer tissues, cell lines (BT-20, HCC-1937, MCF-7, MDA-MB-231, SK-BR-3, T-47D, and ZR-75-1) |
Expression Pattern | up-regulated |
Function Description | High levels of LincIN expression are frequently observed in tumors compared to adjacent normal tissues, and are strongly associated with aggressive breast cancer. |
Pubmed ID | 28558830 |
Year | 2017 |
Title | LincIN, a novel NF90-binding long non-coding RNA, is overexpressed in advanced breast tumors and involved in metastasis |
External Links
Links for LINCIN | GenBank HGNC NONCODE |
Links for breast cancer | OMIM COSMIC |