Basic Information
| LncRNA/CircRNA Name | LINC-GGTLC1-7 |
| Synonyms | XLOC_013703, lnc-C20orf3-1 |
| Region | GRCh38_20:23985050-23988779 |
| Ensemble | ENSG00000149435 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RNA-seq, qPCR, RNAi, Western blot etc. |
| Sample | cell line (BT474) |
| Expression Pattern | down-regulated |
| Function Description | Four out of the five lincRNAs showed statistically significant up- or down-regulation in response to HER2 depletion by RT-qPCR similar to what we observed by RNA-seq analysis. |
| Pubmed ID | 25749757 |
| Year | 2015 |
| Title | Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer. |
External Links
| Links for LINC-GGTLC1-7 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |